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Mechanism Uncovered for Major Genetic Risk Factor of Alzheimer's Disease
ScienceDaily (Oct. 13, 2010) — Alzheimer's disease (AD) is an extremely complicated disease. Several proteins seem to be involved in its cause and progression. For example, the lipid-transport protein apolipoprotein E4 (apoE4) is the major genetic risk factor for AD, and apoE4 carriers account for 65-80% of all Alzheimer's cases, but exactly how apoE4 contributes to the disease is unclear.
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